|
Symbol Name ID |
Apoe
apolipoprotein E MGI:88057 |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Macular hemorrhage |
Conjunctivitis |
Keratoconjunctivitis sicca |
Abdominal aortic aneurysm |
Premature coronary artery atherosclerosis |
Foam cells |
Stroke |
Hypertension |
Sudden cardiac death |
Myocardial infarction |
Lymphadenopathy |
Splenomegaly |
Iris hypoperfusion |
Retinal vein occlusion |
Facial erythema |
| Disease(s) Associated with APOE | |||||||||||||||
| abdominal aortic aneurysm | |||||||||||||||
| age related macular degeneration 1 | |||||||||||||||
| atopic dermatitis | |||||||||||||||
| cerebral infarction | |||||||||||||||
| coronary artery disease | |||||||||||||||
| exfoliation syndrome | |||||||||||||||
| familial combined hyperlipidemia | |||||||||||||||
| multiple myeloma | |||||||||||||||
| sea-blue histiocytosis | |||||||||||||||
| Sjogren's syndrome |
| Mouse Phenotypes | abnormal susceptibility to atherosclerosis |
decreased susceptibility to atherosclerosis |
increased susceptibility to atherosclerosis |
abnormal aorta wall morphology |
abnormal kidney arterial blood vessel morphology |
abnormal spiral modiolar artery morphology |
spiral modiolar artery stenosis |
arteriosclerosis |
atherosclerotic lesions |
dilated glomerular capillary |
kidney microaneurysm |
vascular stenosis |
decreased cardiac muscle triglyceride level |
increased heart weight |
cardiac hypertrophy |
abnormal blood flow velocity |
increased cardiac output |
increased cardiac stroke volume |
decreased systemic vascular resistance |
abnormal blood vessel physiology |
impaired blood-brain barrier function |
abnormal vascular smooth muscle physiology |
abnormal vasodilation |
decreased vasodilation |
blood vessel inflammation |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||
| Apoeshl/Apoeshl | ! | |||||||||||||||||||||||||
| ApoeTg(rtTA)1Gaga/ApoeTg(rtTA)1Gaga | ||||||||||||||||||||||||||
| Apoetm1Bres/Apoetm1Bres | ||||||||||||||||||||||||||
| Apoetm1Unc/Apoetm1Unc | ||||||||||||||||||||||||||
| Apoetm1Unc/Apoetm1Unc Tg(Cyp21a1-Apoe)614Fet/0 |
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| Apoetm1Unc/Apoetm1Unc Tg(Cyp21a1-Apoe)619Fet/0 |
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| Apoetm4Mae/Apoetm4Mae | ||||||||||||||||||||||||||
| Apoetm1Lmh/Apoe+ | ||||||||||||||||||||||||||
| Apoetm1.1Mae/Apoetm1.1Mae Tg(Fabp4-cre)1Rev/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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